Hydroxypropyl Cellulose – HPC

◆ Name: Low Substitue-Hydroxpropyl Cellulose (L-HPC)
◆ Category: Pharmaceutic adjuvant
◆ Character:White or off-white powder,no smell,tasteless;insoluble in ethanol, acetone and ether.
◆ CAS No:9004-64-2
◆ Execution standard:CP2015,USP
◆ Packing specification:25kg/barrel;25kg/bag
◆ Note:
◆ Referred to as”:L-HPC
◆ Use:

Character White or off-white powder,no smell,tasteless;insoluble in ethanol, acetone and ether.
Application Mainly used as disintegrant and adhesive of solid dosage. Its powder has a large surface area and porosity so that accelerates the absorption temperature,increasing the swelling property which makes tablet easy to collapse. In the meanwhile, a larger mosaic effect among its rough structure,drugs and particles improvs the hardness and gloss of the tablet. To the drug that cannot easily be shaped, it will promote it molding, improve its hardness. To the drug with poor disintegrating property, it will accelerate the collapse so that improve the dissolution to enhanced bioavailability.
Type Application Assay Particle
LH11 Disintegrant to prevent the tablet crack and for direct compression.  10.0-12.9% 55μm
LH21 Disintegrant and adhesive to tablet by wet granulation 10.0-12.9% 45μm
LH22 Normal disinterating property, used while no need of strong cohesive force. 7.0-9.9% 45μm
CAS 9004-64-2
Specification CP2015,USP
Package 25kg/barrel;25kg/bag
  • Download PDF FileH-HPC 3000CPS
  • Download PDF FileH-HPC L
  • Download PDF FileL-HPC LH21
  • Download PDF FileL-HPC LH11
  • Download PDF FileL-HPC LH22

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