Application of Sodium carboxymethyl cellulose in Pharmaceutical Industry
In the pharmaceutical industry, Sodium carboxymethyl cellulose can be used as emulsion stabilizer of injections, the adhesion and film-forming agents of tablets. Animal experiments have shown that sodium carboxymethyl cellulose is a safe and reliable carrier of anticancer drugs.
sodium carboxymethyl cellulose can be used to make film-forming materials. The animal model researches have shown that the film can be effective in the control of wound infection. It has no significant differences compared with gauze wound dressings, but the film is obviously superior to gauze dressings in controlling the exudation of wound interstitial fluid and quick healing of wound. Moreover, it can reduce postoperative edema and wound stimulation phenomena.
The best prescription is the film agent made by polyvinyl alcohol (PVA), sodium carboxymethyl cellulose (CMC) and carboxyl polymethyl (CP) with the ratio of 3:6:1. Both the adhesive ability and release rate can be increased. Furthermore, it helps to significantly improve the adhesion ability of sustained-release film agents of mucosa, extend the resistance time of preparation in the mouth cavity and enhance the drug efficacy of preparation.
Some studies have shown that sodium carboxymethyl cellulose is superior to sodium hyaluronate in reducing postoperative peritoneal adhesion, so can be an effective way to prevent the occurrence of peritoneal adhesion. In the treatment of liver cancer, sodium carboxymethyl cellulose can be used in transcatheter arterial perfusion anticancer drugs to significantly extend the resistance time of anticancer drugs in the tumor, enhance antineoplastic function and improve therapeutic efficacy. In addition, sodium carboxymethyl cellulose has wide application in animal medicine.
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